Xeomin Compared to Botox & Dysport

We have all three new formulas for injection in our office. Botox, Xeomin, and Dysport are similar, with slighty different formulations and different manufacturers. Here, we will discuss Xeomin compared to botox and Dysport compared to botox.

A woman looking forward to her appointment to receive the Botox treatment.The day after this woman's Botox injection.


Injection of Botox, Xeomin, Dysport

Dr. Wright is a skilled, experienced injector of botulinum injectibles. Please note that injectibles are recommended by their manufacturers to be utilized by physicians. Knowledge of facial anatomy and musculature is necessary for expert injection. This is not a beautician or aesthetician treatment.

Dr. Wright has a nimble touch injecting, producing smoothness with no “frozen” areas. There is no droop or “surprised” look with his technique. He and our trained RNs meticulously plan the treatment to isolate frown-producing muscles for relaxation. This has given his many injectible patients a wonderful treatment. We are a popular provider of Xeomin, Botox and Dysport in St. Louis and St. Charles.

The type of lines that Dysport is known to help eliminate.What this woman's face looks like after she used Dysport.


Botulinum toxin as a cosmetic treatment has been around for quite some time. It is a purified protein derived from bacteria. Its first therapeutic use, in the 1980s, was in treating crossed eyes and rapid blinking. In 1989, studies first emerged about its effectiveness easing wrinkle lines when injected into facial muscles. The Botox craze was born.

Woman frowning because she has not had her Xeomin injections yet. Woman very pleased with the effects of her Xeomin injections.

Botox — the botulinum injectables — are not fillers or plumpers. They do not add volume or puffiness. They inhibit the frown action. Botox is perhaps the best-known botulinum toxin formulation and has been around commercially the longest. Officially a neurotoxin, meaning an inhibitor of nerve tissue function, Botox is widely used to treat wrinkles. It works by blocking the signal to “contract!” or “scowl!” from the brain to the muscle. This eases the place in the skin where the scowl or frown has etched a wrinkle. Without the frowning motion, the skin is smooth for the duration of the injection’s effectiveness — usually 3 to 4 months.

Recently, two new botulinum toxin formulations have received FDA approval for cosmetic treatment. Both Xeomin (ZEE-oh-min) and Dysport (DIS-port) are treatments that, like Botox, use botulinum toxin for the treatment of wrinkles (and excessive sweating and some jaw disorders).

A funny picture about the effects of Botox when used incorrectly.


Xeomin, newly announced from Merz Pharmaceuticals, is a botulinum toxin preparation that is used at the same rate as Botox cosmetic. The necessary doses of xeomin compared to botox are identical.  However many units a patient required of Botox, he or she will receive the same number of Xeomin units. If a patient responded well to 22 units of Botox, she will respond well to 22 units of Xeomin.

Her face prior to the application of Dysport injections. What here face looks like after her Dysport injections.

Dysport, another Botox alternative, is administered somewhat differently. Approximately 2.5 units of Dysport correspond to one unit of Botox or Xeomin. If a patient responded to 22 units of Botox, she will respond to 55 units of Dysport.

We study facial anatomy carefully before injecting, calculating the best application of the injections so as to maximize wrinkle suppression while preserving natural facial animation.


Botox and Dysport vials contain, in addition to the botulinum toxin, a substance called albumin. This is a protein found in the blood. Its presence in Botox and Dysport vials makes the chemical stay stable in its jar between uses. Xeomin, on the other hand, just contains boltulinum toxin and has no additives.

Some people feel that when Botox “does not work,” Dysport does and vice versa. Some patients have a much quicker response to Botox and Xeomin than to Dysport, and some to Dysport before Xeomin and Botox. For those experiencing less of a result with Botox than they are used to, Dysport is a wonderful change.

Side Effects

All botulinum toxin formulations carry some risk of side effect with treatment. These include dry mouth, fatigue, headache, nausea, neck pain, pain, redness, bleeding at injection site, swelling, or tenderness at the injection site, sinus inflammation, sore throat, stiff or weak muscles at or near the injection site. Very rare but serious side effects include allergic reactions, difficulty swallowing or breathing, dizziness, drooping affected area, facial paralysis, fainting, loss of bladder control, loss of strength, seizures, severe or persistent muscle weakness, shortness of breath, slow heartbeat, speech changes or problems, vision changes or problems, wheezing.